I decided to go through the U.S. Routes to find disagreements with the underlying state route files.
US 1/US 221: LFBriAPRd -> CamRd
US 1/540: SteMatRd ->
WooAcaRdUS 17: GA25SprDar -> FortGeoDr
US 17: GA57/99 -> GA99 (or GA99_Eul?)
US 19: move GA208 to match point on 3 and 208
US 19/3: GA20Con ->
LowWooRdUS 19/US 29/US 41: starting at CleAveSW and ending at MackDobRdNW, remove directional suffixes; also McDStSW -> McDanSt (or on 3, McDanSt -> McDSt)
US 19: GA141 -> GA141_S
US 19: GleDrNE -> GleDr, and many other suffixes here that are in both the US 19 and 9 files
US 19: add missing points (from 400's file) between GA136 and GA60_S
US 23/US 341: LivRarmRd -> OweRd
US 23: GA13/155 -> GA13_S
US 23: replace +X007(US23) with GA87ConEas to match the EasByp point on 87
US 23/US 129altmac: WillHenRd -> AlbJenRd? neither is posted
US 23/US 129altmac/87: GA87Con -> GA87ConMac
US 23: I-75(167A) -> *I-75(167A), move I-75(167) to match 87
US 23: I-675(2) -> I-675
US 23: EllRd -> ForPkwy
US 23: I-20(60) -> I-20
US 23: I-85(91) -> I-85
US 23: replace +X021(US23) with MudCreRd to match 365
US 23/US 441: LevGroRd -> GA15Con
US 25: move GA121_S to match 67
US 25: move GA88 to match 121
US 27: PhiRd -> CouLineRd
US 27: WestRomeByp -> GA1Lp_S, GA1Lp -> GA1Lp_N
US 27: RivPkwyNE -> RivPkwy
US 27: McFAve -> McFarAve_S, DodAve -> McFarAve_N
US 29/139: NavAve ->
HarShePkwyUS 29: starting at RocRdNW and ending at GloRdNW, remove directional suffixes
US 29: GA20/124_N -> GA20/124
US 29: replace +X011(US29) with DroCreRd to match 316
US 29/US 129/US 441: PetSt -> GA10Lp(9)
US 41: MainSt -> MainSt_Lak
US 41: OldUS41 -> FoxAve
US 41: KinBrgRd -> CenAve
US 41: 11thStS -> JoeWriDr
US 41: 6thSt -> 7thSt??
US 41: W11thSt -> 11thSt
US 41: US341 -> US341_Per
US 41: RicPetBlvd ->
LowWooRdUS 41: WWesRdNW -> WesRd
US 41: GA176 -> MarsHillRd
US 41: RedTopMRdSE ->
RedTopConnUS 41: RivRd -> OldRivRd
US 41/US 76: HosCon -> ChaRd
US 76: SMainSt -> MainSt_Eli
US 76/515: OrvLaneDr -> OrvLanCon
US 76: US19_N -> US19/129_N, US19_S -> US19/129_S
US 76: GA17/515_N -> GA17/515
US 78: MirBlvd -> GA8Con
US 78/US 278: CopLakeRd -> CooLakeRd
US 78: GA22_N -> GA22_E
US 78: GA77_W -> GA77_S, GA77_E -> GA77_N
US 78/10: GA22_S ->
GA22_WUS 78: WillWinRd -> WillWynRd
US 80: I-16 -> I-16(2)
US 82: InnSt -> InmSt
US 82: I-95(29) -> I-95
US 129: MackHEnRd -> MackHenRd
US 129: HouRd_N -> HouRd
US 129/11/49: I-16 (1A) -> I-16
US 129: AppPkwy -> US129BypCle_S, HulRd -> US129BypCle_S
US 278: GA260 -> GleRd
US 280: I-185(1) -> I-185
US 280: WallSt -> WallSt_W
US 280: GA215_W -> GA215_N, GA215_E -> GA215_S
US 301: LakRd -> ParSt_W
US 319: US84BusTho_W -> US84Bus
US 319: US441BypDub_S -> US441Byp
US 319: RubyDr -> NewChuRd
US 341: US341Bus_N -> US341BusEas_N
US 341: replace +X013(US341) with MorDr to match 11busper
US 341: US41 -> US41_Bar
US 441/29: FallLineFwy -> GA540
3: RedTopRd ->
RedTopConn4: GA4BusWad_* -> US1BusWad_*
4: WooDr ->
WooAcaRd5/515: OldUS76 -> BalRd
10: GA44_W ->
GA44_S11: GA11Byp_S -> GA11/135Byp
11: US129BusCle_* -> US129BypCle_*
11: US341/341Byp -> US341_N
12: WireRd_W -> WireRd
14: NabAve ->
HarShePkwy15: OldUS441Cen_N -> OldUS441_Cen
15: OldUS441Com_N -> OldUS441_Com
20: RicPetBlvd ->
LowWooRd22: move US129_N to match US 129 and 44
23: US301_N -> US1/23_N
25: GA57 -> GA99 (or GA99_Eul?)
27: US129_S -> US129/129Bus
30: US80/280 -> US80_W
35: US84Bus_W -> US84Bus
47: US78/378 -> US78
75altcle: GA75Con -> US129Byp
87: EasByp -> GA87ConEas
87ConEas: create a file and add a point on US 341/27
87: OldGA361 -> BassRd
115: AppPkwy -> US129Byp and move to match
282: OldGA5 -> MainSt
282: GA2 -> GA2_W
520: WallSt_N -> WallSt_W, WallSt_S -> WallSt_E