In preparation of the new I-69 river crossing, US-41 has been rerouted to the new the new I-69 alignment between "KY351" & "US60/41Alt". This can be seen as open in the 'ESRI World Imagery' layer. Two new 'closed' points will be required for US-41, as this is a decent reroute.
OSM also claims that the road is now also I-69 up & open to US-60, but I'm not sure about this part. The only safe thing to do is the US-41 reroute above for sure.